POU1F1 Antikörper (C-Term)

Produktnummer ABIN1108699

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch POU1F1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Schwein und Huhn.

Kurzübersicht für POU1F1 Antikörper (C-Term) (ABIN1108699)

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POU1F1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-POU1F1 Antikörper

Bindungsspezifität: C-Term

Sequenz: QEIMRMAEEL NLEKEVVRVW FCNRRQREKR VKTSLNQSLF SISKEHLECR

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, Bovine, Pig, ChickenSpecies reactivity (tested):Human

Aufreinigung: Purified on peptide immunoaffinity column

Immunogen: The immunogen for anti-POU1F1 antibody: synthetic peptide directed towards the C terminal of human POU1F1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Haltbarkeit: 12 months

Details zu POU1F1

Target: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Andere Bezeichnung: POU1F1

Hintergrund: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.Synonyms: GHF-1, GHF1, Growth hormone factor 1, PIT-1, PIT1, Pituitary-specific positive transcription factor 1

Gen-ID: 5449

NCBI Accession: NP_000297

Pathways: Regulation of Carbohydrate Metabolic Process